PAGET'S DISEASE
Another disease found in the skeletal system is Paget’s disease. The bones break down faster than they are able to rebuild. With the accelerated breakdown of bones occurring in Paget’s disease, there is an increased risk of fracture that results in fragile bones. As stated by Rodan & Martin (2000),
It is marked by an increase in osteoclast numbers and activity
and often affects multiple sites throughout the skeleton.
Increased bone resorption is met by a compensatory increase in bone
formation and local bone turnover, leading to woven bone, which is bulky, weak, and prone to bowing and fracture.
(p.1509)
It is most likely for Paget’s disease to occur in the skull, spine, legs and pelvis. As individuals become older the risk of Paget’s disease increases. Also if another family member has been diagnosed with this disease the risk of one having the disease increases. Along with having fragile bones other complications of Paget’s disease also include hearing loss, pinched nerves in the spine and broken bones.
It is marked by an increase in osteoclast numbers and activity
and often affects multiple sites throughout the skeleton.
Increased bone resorption is met by a compensatory increase in bone
formation and local bone turnover, leading to woven bone, which is bulky, weak, and prone to bowing and fracture.
(p.1509)
It is most likely for Paget’s disease to occur in the skull, spine, legs and pelvis. As individuals become older the risk of Paget’s disease increases. Also if another family member has been diagnosed with this disease the risk of one having the disease increases. Along with having fragile bones other complications of Paget’s disease also include hearing loss, pinched nerves in the spine and broken bones.